Polyphenols and Flavanoids

Polyphenols and Flavonoids—What They Are and How They Benefit Your Health

The primary ingredient in BergaMet products is Bergamot Polyphenol Fraction (BPF). Bergamot is a citrus fruit grown in the Calabria region of southern Italy, but what exactly is a polyphenol?

Polyphenols are phytochemicals found abundantly in plants that are antioxidants. Antioxidants can be divided into three primary groups:

  • Carotenoids
  • Allyl Sulfites
  • Polyphenols

The role of antioxidants is to protect the trillions of cells in your body from free radical damage. If the cells in your brain and body don’t get the adequate protection they need to function properly, aging accelerates and you are at much greater risk of developing diseases such as cancer, cardiovascular disease, Alzheimer’s, dementia, and other serious illnesses. Therefore, the antioxidant role of polyphenols is essential to a healthy mind, body, and quality of life.

Types of Flavonoids and Polyphenols

Polyphenols are micronutrients with antioxidant activity. More than 8,000 types of polyphenols have been identified and are found most abundantly in whole foods such as dried spices, fruits, vegetables, red wine, and cocoa. Polyphenols can be divided into four categories:

  • Flavonoids
  • Stilbenes
  • Lignans
  • Phenolic Acids

Flavonoids are divided into six subclasses: flavanones, isoflavones, anthocyanins, flavonols, flavanols and flavones.

Citrus bergamot is characterized for its unique profile of flavonoids. Bergamot (Citrus bergamia) juice is comprised of a particularly high content and a unique composition of flavonoids, including relatively rare neoeriocitrin and neohesperidin. As recently discovered and reported in the study Molecular mechanisms of lipid- and glucose-lowering activities of bergamot flavonoids, bergamot juice also contains the rare brutieridin and melitidin flavonoids.

Polyphenols—a Powerhouse of Prevention


Polyphenols are powerful antioxidants. The health benefits and biological properties of polyphenols have been studied extensively for their protective roles, which include:

  • Reducing inflammation
  • Protecting the cardiovascular system
  • Supporting healthy blood sugar and blood pressure levels
  • Preventing growth of cancer cells
  • Protecting against free radicals and UV rays, reducing premature aging
  • Protecting and nourishing brain cells to protect against dementia and other brain/nervous system disorders
  • Increasing the ratio of beneficial bacteria in the gut (prebiotic)

Polyphenols Protective Role in Preventing Diseases


The protective qualities of polyphenols have also been studied extensively for their role in preventing specific diseases. More research is needed to understand the effects of polyphenols on specific diseases, but what is known so far is substantial.


Cardiovascular Disease

Flavonoid polyphenols improve cellular function in your arteries and veins. Polyphenols reduce vascular endothelial growth factor, which leads to plaque in the arteries. Polyphenols are an antioxidant, reducing inflammation.


Type 2 Diabetes

Polyphenols have been found to stabilize metabolism of blood sugar and fat, lower inflammation, and reduce insulin resistance. The preventative qualities of polyphenols may reduce the risk of cardiovascular disease from diabetes.



Inflammation and oxidative stress are closely linked. Many studies have proven the beneficial effect polyphenols play on free radicals and inflammation. Prolonged, low-grade inflammation leads to chronic illness including diabetes, rheumatoid arthritis, cardiovascular diseases, alcoholic liver disease, and other diseases.


Many research studies have shown that the protective, antioxidant qualities of polyphenols may protect against cell damage that can trigger cancer development. Polyphenols also reverse genetic DNA markers that could reduce growth of tumors.


Alzheimer’s Disease and Dementia

Clinical studies have shown that the daily consumption of polyphenols reduce the progression of dementia. The neuroprotective qualities of polyphenols may reduce the risk of developing Alzheimer’s and other mentally degenerative diseases.

Citrus Bergamot Fruit

Citrus Bergamot—A Polyphenol Super Fruit


BergaMet supplements are made from bergamot (Citrus bergamia) juice, which has a particularly high content and a unique composition of flavonoids.

The flavonoid content in 42 citrus species has been studied extensively. Studies confirm the amount of flavonoids per volume unit of juice is absolutely the highest in bergamot compared to other citrus fruits. Bergamot is characterized for its unique profile of flavonoids, as well as its particularly high content and quality.

BergaMet supplements are made with a patented process that compresses polyphenol-enriched powder, containing over 40% flavonoids, into Bergamot Polyphenol Fraction (BPF) tablets. BPF contains the same flavonoids as Bergamot juice, but at much higher levels. Bergamot Polyphenolic Fraction is 200 times more concentrated in BPF tablets.


Discover how the most powerful citrus bergamot product in the world can improve your energy, health and well-being.

* Results may vary from person to person. Always consult your Doctor if unsure.

This product does not claim to treat, diagnose or cure any diseases. BergaMet is a supplement and has not been approved by the FDA.