Background: BPF (bergamot polyphenolic fraction) was been obtained from peeled-off fruits by industrial pressing and squeezing. The main polyphenol components of bergamot polyphenolic fraction BPF are flavonoids, and their composition basically mirrors the bergamot juice profile. Certain individual flavonoids present in BPF were studied by Dr. Elzbieta Janda, of the Institute of Research for Food Safety & Health (IRC-FSH), Campus Germaneto, Catanzaro, Italy, and Dr. Ross Walker, of the Sydney Adventist Hospital, Sydney, Australia, who found that these BPF flavonoids are implicated in the regulation of several metabolic enzymes, expressed in the liver, blood and endothelial cells.
Background: Cholesterol levels and blood glucose levels are important markers and risk factor indicators for various cardiovascular and heart health concerns. Experimental and epidemiological evidence suggests that dietary polyphenols, such as flavonoids, may help regulate these risk factors to support maintenance of normal homeostasis. This has been exploited in the case of bergamot juice flavonoids and proved to work in clinical practice by Dr. Ross Walker, Consultant Cardiologist, Sydney Adventist Hospital, Sydney, Australia and others.
Background: A 6 month study of the use of concentrated citrus bergamot juice from which an isolated polyphenol fraction (BPF) evaluated the impact of Bergamot Polyphenol Fraction on regulation of total cholesterol levels, levels of both LDL and HDL cholesterol, triglyceride levels, and glucose levels.
Background: Statins are the most commonly prescribed drugs to reduce cardiometabolic risk, yet some patients experience statin-induced unpleasant side effects. A study was conducted by Dr. Micaela Gliozzi and Dr. Saverio Muscoli (Department of Medicine, Chair of Cardiology, University of Rome Tor Vergata, Rome, Italy) to look at the use of natural bergamot-derived polyphenols in individuals undergoing statin treatment to regulate target lipid values.
It was found that the addition of BPF to statins significantly enhanced regulation of normal serum lipid profiles compared to statins alone. This effect suggests a multi-action enhanced potential for BPF in patients on statin therapy.
To read the full study, Google: “Micaela Gliozzi, Bergamot Polyphenolic Fraction, International Journal of Cardiology 2013”.
Background: In a double-blind, placebo-controlled clinical study on 107 individuals at the San Raffaele Scientific Institute for Research, Hospitalization and Health Care (San Raffaele IRCCS, Rome), Drs. Micaela Gliozzi and Cristina Carresi, et al., examined the effect of Bergamot extract containing Bergamot Polyphenolic Fraction on biomarkers of LDL cholesterol levels, and cardiovascular risk factors.
Background: Cardiovascular conditions are closely associated with obesity as well as type 2 diabetes. Recent studies highlight a relationship between dietary factors and cardiovascular health, but the characteristics of an optimal diet have yet to be better clarified. Increasing experimental and epidemiological evidence suggests that dietary polyphenols, in particular flavonoids, such as Bergamot Polyphenol Fraction, may play an important role in regulating normal broad anti-oxidant activity, and has been also shown to modulate metabolic enzymes. Bergamot juice is rich in these flavonoids and exhibit statin-like proprieties. Recently, the potential of bergamot derivatives has also been investigated in human studies.
Background: Bergamot juice produces lipemic-regulating activity, though the mechanism remains unclear. In this study, Dr. Vincenzo Mollace of the Department of Pharmacobiological Sciences, University Magna Graecia, Catanzaro, Italy, and Dr. Saverio Muscoli, of the Department of Cardiology, Tor Vergata University, Rome, Italy, investigated the effect of bergamot extract – Bergamot Polyphenol Fraction (BPF) in 237 patients with cholesterol concerns.
Background: Aerobic capacity and endothelial function represent major determinants of exercise performance in athletes being improved by physical training. This improvement is the result of adaptive changes in skeletal muscle, mostly due to their ability to use oxygen to generate energy for muscle work.
Background: Limited research has assessed the value of polyphenol supplements in neurological function and sports reaction measures. A highly concentrated extract of citrus bergamot polyphenols was tested because of extensive publications demonstrating benefits in oxidative stress and regulation of normal lipid and cholesterol levels, and therefore might impact visual components.
Background: Menopause is natural phenomenon in women that typically occurs in the early 50s. It is associated with additional health concerns for women that affect general wellbeing, fitness and quality of life, as well as complicating the aging process. Many menopausal women exercise yet note that both physical and psychological results lag behind typical results before menopause.
Background: Erectile dysfunction (ED) is a common condition, and a seminal study –The Massachusetts Male Aging Study – is often cited by experts in discussions of prevalence. This study found that around 52 percent of men experience some form of ED, which is also highly correlated with various cardiovascular concerns.
A study conducted by Dr. Vincenzo Mollace and others, of the Institute of Research for Food Safety & Health in Catanzaro, Italy, looked at the impact of bergamot polyphenolic fraction (BPF 47%), a natural antioxidant known to regulate normal serum lipids and glucose. The effect of BPF alone or in combination with Tribulus terrestris and Epimedium extract in supporting endothelial function and reactive vasodilatation has been explored after 120 days of use, and showed significant impact in regulating normal healthy erectile function in men by supporting normal endothelial function and penile arteriolar blood flow.
To read the full study, Google: “Vincenzo Mollace, Bergamot Polyphenolic Fraction, Pharma Nutrition”.
BergaMet is the only company whose bergamot extract is approved by the prestigious Accademia del Bergamotto in Calabria, Italy.
The Calabrian region of Italy yields the most potent citrus bergamot fruit in the world, which enables BergaMet to produce a BPF (bergamot polyphenolic fraction) of 47 percent or greater - the most concentrated extract available anywhere.
Competing citrus bergamot products contain only 38 percent BPF or less (BergaMet products include a minimum of 40 percent and up to 47 percent BPF).
Bergamot is naturally sourced, organic, and grown with no pesticides whatsoever.
BergaMet is the only bergamot product formulated based on the most up-to-date research by highly regarded medical professionals who oversee thousands of patients currently taking bergamot supplements.